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Simparica Trio Extra Large Dogs 88.1 132 lbs Red is a once-monthly chew that protects against fleas, ticks, heartworm disease, and common intestinal worms. Each dose contains 72mg sarolaner, 1.44mg moxidectin, and 300mg pyrantel to quickly kill fleas within 4 8 hours and provide persistent protection for up to 5 weeks. It also kills mosquitoes (Aedes aegypti) and heartworm microfilariae for added protection.
Regular monthly administration prevents heartworm disease while treating and controlling hookworms and roundworms, including immature and adult stages. By breaking the flea life cycle and reducing environmental contamination, it helps lower the risk of reinfestation and supports overall parasite management.
| Animal Type | Dog |
|---|---|
| Ingredients | 300 mg pyrantel (as embonate) 72mg sarolaner 1.44 mg moxidectin |
| Directions for use | Dosage:
Administration:
|
| Caution | Caution is advised when administering Simparica Trio to dogs with a history of seizures. Sarolaner, an isoxazoline ingredient in the product, has been associated with neurologic adverse reactions including tremors, loss of coordination (ataxia), and seizures. Such reactions may occur in dogs with or without prior neurologic disorders. The product has not been evaluated for safety in breeding, pregnant, or lactating dogs. Vomiting and diarrhea were the most commonly reported adverse reactions during clinical trials. |
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